Everyone knows the phrase “indica puts you in-da-couch.” Honestly, it’s a corny phrase to say to patients, but it also does the job of explaining the different effects of smoking indica vs. sativa.

Cannabis Strains Explained

Indica strains of cannabis make you feel relaxed, sleepy and calm. Sativa strains make you feel happy, energetic, and social. For most people, this is enough of an explanation to help them pick an effect they are looking for when they buy medical cannabis. But for me, I want to know the scientific reason for an indica vs. sativa high. So let’s break this down into the specific cannabinoids that are present in each form of marijuana.

9THC

THC is the molecule that gets you stoned. It binds to the CB1 receptor and gives you that euphoric sense of well-being and is great for pain relief.

INDICA

CBD

Cannabidiol (CBD) is non-psychoactive. It acts as an antagonist for the CB1 receptor and has a great anti-anxiety effect.

Strains to look for:
ACDC
Harmony Rose
Harlequin

CBN

Cannabinol (CBN) is non-psychoactive. It is a powerful sedative and great for pain relief.

Strains to look for:
Animal Cookies
Girl Scout Cookies
Fire OG

SATIVA

THCV

Tetrahydrocannabivarin (THCV) can have psychoactive properties. Helps intensify the effects of THC. Known to be an appetite suppressant.

Strains to look for:
Durban Poison
Cherry Pie

CBG

Cannabigerol (CBG) is non-psychoactive. It has euphoric and anti-depressant effects.

Strains to look for:
Allen Wrench
Trainwreck
NYC Diesel

CBC

Cannabichromene (CBC) is non-psychoactive. CBC binds poorly to the CB1 receptors in the brain, but does bind to other pathways in the body to enhance the effects of other cannabinoids.

Strains to look for:
3 Kings
Sour Diesel
OG Kush
Headband

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